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Three-dimensional analysis of craniofacial form in a familial rabbit model of nonsyndromic coronal suture synostosis using Euclidean distance matrix analysis.

Authors
  • Burrows, A M1
  • Richtsmeier, J T
  • Mooney, M P
  • Smith, T D
  • Losken, H W
  • Siegel, M I
  • 1 School of Physical Therapy, Slippery Rock University, Pennsylvania 16057, USA. [email protected]
Type
Published Article
Journal
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
Publication Date
May 01, 1999
Volume
36
Issue
3
Pages
196–206
Identifiers
PMID: 10342607
Source
Medline
License
Unknown

Abstract

Results showed that delayed onset synostosis did not produce craniofacial morphology that was different from normal at any age. However, complete synostosis yielded predictable and global craniofacial shape differences at both ages relative to normal skulls, producing an overall shorter, wider cranium with the most markedly compensating regions in a posterosuperior position of the skull. In addition, delayed onset synostosed crania showed no shape differences in the basicranium, relative to normal crania, suggesting primacy of the calvaria in this model of coronal synostosis. However, further investigations are necessary to verify primacy of the calvaria in this model.

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