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Three-component reaction of aryl diazoacetates, alcohols, and aldehydes (or imines): evidence of alcoholic oxonium ylide intermediates.

Authors
  • Lu, Chong-Dao
  • Liu, Hui
  • Chen, Zhi-Yong
  • Hu, Wen-Hao
  • Mi, Ai-Qiao
Type
Published Article
Journal
Organic Letters
Publisher
American Chemical Society
Publication Date
Jan 06, 2005
Volume
7
Issue
1
Pages
83–86
Identifiers
PMID: 15624983
Source
Medline
License
Unknown

Abstract

The Rh(II)-catalyzed three-component reaction of aryl diazoacetates, alcohols and aldehydes was explored, which provided evidence of alcoholic oxonium ylide formation for O-H insertion. A new C-C bond formation reaction where alcoholic oxonium ylides were trapped by electron-deficient aryl aldehydes (or imines) was realized.

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