Affordable Access

[Thoughts and exploration on pharmacokinetic study of herbal medicines based on metabonomics and complex network].

Authors
  • Xiang, Zheng1
  • Cai, Xiao-Jun
  • Zeng, Su
  • 1 School of Pharmaceutical Sciences, Wenzhou Medical College, Wenzhou 325035, China. [email protected] , (China)
Type
Published Article
Journal
Yao xue xue bao = Acta pharmaceutica Sinica
Publication Date
May 01, 2012
Volume
47
Issue
5
Pages
558–564
Identifiers
PMID: 22811996
Source
Medline
License
Unknown

Abstract

The change of drug development pattern pushes the innovation of drug valuation methods. The pharmacokinetic research of traditional Chinese medicines (TCM) is an important part of TCM modernization and plays a key role in novel drug development of TCM. However, the research methods and techniques are in consistent with the specific characteristics of TCM, i.e., multiple-components is still in the infant. This review makes a brief summary of current pharmacokinetic exploration of TCM, metabonomics and complex network, and puts forward a new strategy based on complex network and metabonomics to study TCM pharmacokinetic in order to disclose the active components and mechanism of TCM.

Report this publication

Statistics

Seen <100 times