Affordable Access

deepdyve-link
Publisher Website

Thinness and fecundability: Time to pregnancy after adolescent marriage in rural Bangladesh.

Authors
  • Hur, Jinhee1
  • West, Keith P Jr1
  • Shamim, Abu Ahmed2
  • Rashid, Mahbubur2
  • Labrique, Alain B1
  • Wu, Lee S F1
  • Ali, Hasmot2
  • Ullah, Barkat3
  • Schulze, Kerry J1
  • Klemm, Rolf D W1
  • Christian, Parul1
  • 1 Center for Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
  • 2 The JiVitA Project, Gaibandha, Bangladesh. , (Bangladesh)
  • 3 Department of Nutrition, University of California, Davis, Davis, California.
Type
Published Article
Journal
Maternal & child nutrition
Publication Date
Mar 24, 2020
Identifiers
DOI: 10.1111/mcn.12985
PMID: 32207581
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Undernutrition may affect fecundability, but few studies have quantified this relationship. In rural Bangladesh, where newlywed couples face strong pressures to become pregnant, we assessed fecundability, estimated by time to pregnancy (TTP), and its association with preconceptional thinness among nulligravid, newlywed female adolescents. During 2001-2002, 5,516 newlywed women aged 12-19 years participated in a home-based, 5-weekly surveillance system for 5-6 years to enrol pregnant women into an antenatal vitamin A or β-carotene supplementation trial. Thinness was defined as a left mid-upper arm circumference (MUAC) ≤21.5 versus >21.5 cm. At each visit, staff obtained a monthly history of menstruation. Report of amenorrhea prompted a human chorionic gonadotropin urine test to confirm pregnancy. We derived hazard ratios (with 95% confidence intervals [CI]) for pregnancy and Kaplan-Meier curves for TTP. Ages of women at marriage and pregnancy detection (mean ± standard deviation) were 15.3 ± 1.9 and 17.0 ± 1.9 years, respectively. A total of 82.7% of thinner and 87.3% of better nourished women became pregnant. The unadjusted and multivariable relative hazard of ever becoming pregnant was 0.84 (95% CI [0.78, 0.89]) and 0.86 (95% CI [0.81, 0.92]), respectively, and TTP was 12 weeks longer (median [95% CI]: 63 [58-68] vs. 51 [49-54]) in women whose MUAC was ≤21.5 versus >21.5 cm. In rural Bangladesh, thin adolescent newlywed girls have a lower probability of becoming pregnant and experience a longer time to pregnancy. © 2020 The Authors. Maternal & Child Nutrition published by John Wiley & Sons Ltd.

Report this publication

Statistics

Seen <100 times