Affordable Access

Thermogenetic changes following frontal neocortex stimulation.

Authors
Type
Published Article
Journal
Brain research bulletin
Publication Date
Volume
22
Issue
6
Pages
1003–1007
Identifiers
PMID: 2790492
Source
Medline

Abstract

Heat production changes were recorded in anesthetized female Sprague-Dawley rats after stimulation of orbital frontal neocortex. The results obtained show that orbital frontal neocortex stimulation significantly increases oxygen consumption, and core and brown adipose tissue temperature. The increase was more substantial after stimulation of left than right cortex. Administration of the beta-blocker propranolol abolished the increase in O2 consumption, core and brown adipose tissue temperature following cortical stimulation. These results are in agreement with our previous research showing that functional ablation of cerebral cortex blocked the increase in thermogenesis following lateral hypothalamic lesion. These findings also show that the orbital frontal neocortex in rats is specifically involved in the control of thermogenesis.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments