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Therapeutic Concepts for Oligometastatic Gastrointestinal Tumours

Authors
  • Ricke, Jens
  • Westphalen, Christoph Benedikt
  • Seidensticker, Max
Type
Published Article
Journal
Visceral Medicine
Publisher
S. Karger GmbH
Publication Date
Oct 05, 2020
Volume
36
Issue
5
Pages
359–363
Identifiers
DOI: 10.1159/000509897
Source
Karger
Keywords
License
Green
External links

Abstract

Background: Clinical trials have proven a survival benefit from applying local therapies for oligometastatic cancers of various origin. Summary: Today, the definition of oligometa­static disease is based on limited lesion numbers and organ systems involved. Treatment guidelines by the European Organisation for Research and Treatment of Cancer (EORTC), European Society for Medical Oncology (ESMO) and several other groups suggest a threshold of up to 5 tumours. Established biological markers indicating the aggressiveness of a given tumour (and therefore suggesting local treatment only or the addition of or complete switch to systemic therapies) are missing, except for disease-free survival, the only recommended parameter for patient selection beyond lesion count. Key Message: The following article discusses clinical implications as well as local techniques established for the treatment of oligometastatic disease.

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