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The SBASE protein domain library, release 8.0: a collection of annotated protein sequence segments

Authors
  • János Murvai
  • Kristian Vlahovicek
  • Endre Barta
  • Sándor Pongor
Publisher
Oxford University Press
Publication Date
Jan 01, 2001
Source
PMC
Keywords
Disciplines
  • Biology
  • Computer Science
License
Unknown

Abstract

SBASE 8.0 is the eighth release of the SBASE library of protein domain sequences that contains 294 898 annotated structural, functional, ligand-binding and topogenic segments of proteins, cross-referenced to most major sequence databases and sequence pattern collections. The entries are clustered into over 2005 statistically validated domain groups (SBASE-A) and 595 non-validated groups (SBASE-B), provided with several WWW-based search and browsing facilities for online use. A domain-search facility was developed, based on non-parametric pattern recognition methods, including artificial neural networks. SBASE 8.0 is freely available by anonymous ‘ftp’ file transfer from ftp.icgeb.trieste.it. Automated searching of SBASE can be carried out with the WWW servers http://www.icgeb.trieste.it/sbase/ and http://sbase.abc.hu/sbase/.

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