THE ROLE OF TISSUE PERMEABILITY WITH PARTICULAR REFERENCE TO THE BLOOD-BRAIN BARRIER IN DISEASES OF THE CENTRAL NERVOUS SYSTEM

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THE ROLE OF TISSUE PERMEABILITY WITH PARTICULAR REFERENCE TO THE BLOOD-BRAIN BARRIER IN DISEASES OF THE CENTRAL NERVOUS SYSTEM

Publication Date
Source
PMC
Keywords
Disciplines
  • Design
  • Medicine
  • Pharmacology
License
Unknown

Abstract

hospital protocol.qxd Reflex Sympathetic Dystrophy(RSD) also known as Complex Regional Pain Syndrome (CRPS) is a chronic condition characterized by severe burning pain, patho- logical changes in bone and skin, excessive sweating, tissue swelling and extreme sensitivity to touch. People afflicted with RSD/CRPS are extraordinarily sensitive to certain stimuli, such as touch, movement, and injec- tions. Patient Tips 1. Bring a written copy of your medication regime. It is important to verify whether your medication regime can be taken care of solely through use of the hospital's pharmacy. Some medications may not be part of the hospital's formulary. 2. Avoid having ice applied to the RSD-affected limb 3. Instruct all hospital staff to always ask before touch- ing you! 4. Request that the surgery protocols be adjusted so that the pre-op shave be done after anesthesia (catheter is in place for epidural or whatever). It feels like a lawnmower has been run over your legs when they shave without anesthesia. Patient Room 1. Whenever possible patient should be in a quiet part of the hospital 2. In a semi-private room, patient should be in the sec- ond bed to avoid inadvertent bumping 3. A Zone-Air bed should be used (adjust mattress pres- sure to patient preference) 4. Heat and air conditioning should be well regulated 5. Standing orders should be issued for patients to have warm blankets 6. Foot Cradle to hold bed linens off body area (will diminish tactile stimuli) 7. Frequent linen changes may be necessary due to hyperhidrosis (increased sweating). 8. Allow family members to bring in clean sheet and pil- lowcases for patient. Hospital sheets are not soft and can irritate the skin. 9. Place a sign above bed designating affected limb Procedures 1. Perform a phlebotomy on unaffected limb only 2. Use Pediatric needles (any trauma can cause the spread of RSD to a new site) 3. Warm Alcohol or Betadine wipes with warm running water on outside of package before

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