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The role of image guided biopsy targeting in patients with atypical small acinar proliferation.

Authors
  • Raskolnikov, Dima1
  • Rais-Bahrami, Soroush1
  • George, Arvin K1
  • Turkbey, Baris2
  • Shakir, Nabeel A1
  • Okoro, Chinonyerem1
  • Rothwax, Jason T1
  • Walton-Diaz, Annerleim1
  • Siddiqui, M Minhaj1
  • Su, Daniel1
  • Stamatakis, Lambros1
  • Yan, Pingkun3
  • Kruecker, Jochen3
  • Xu, Sheng4
  • Merino, Maria J5
  • Choyke, Peter L2
  • Wood, Bradford J6
  • Pinto, Peter A7
  • 1 Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • 2 Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • 3 Philips Research North America, Briarcliff Manor, New York.
  • 4 Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; Clinical Center, National Institutes of Health, Bethesda, Maryland.
  • 5 Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
  • 6 Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; Clinical Center, National Institutes of Health, Bethesda, Maryland.
  • 7 Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; Clinical Center, National Institutes of Health, Bethesda, Maryland. Electronic address: [email protected]
Type
Published Article
Journal
The Journal of urology
Publication Date
February 2015
Volume
193
Issue
2
Pages
473–478
Identifiers
DOI: 10.1016/j.juro.2014.08.083
PMID: 25150645
Source
Medline
Keywords
License
Unknown

Abstract

When magnetic resonance imaging/transrectal ultrasound fusion guided biopsy detects isolated atypical small acinar proliferation on index biopsy, early rebiopsy is unlikely to detect clinically significant prostate cancer. Cores that retarget areas of previous atypical small acinar proliferation are more effective than random rebiopsy cores.

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