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The identity of a myelin-like fraction isolated from developing brain

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PMC
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  • Biology
  • Chemistry

Abstract

1. A myelin-like membrane fraction was isolated from developing rat brain by a new method. 2. The chemical composition and morphology of the fraction are described. 3. The myelin-like fraction is similar to myelin in characteristic enzyme activity but differs in the absence of basic protein and cerebrosides. No similarity to other subcellular fractions was observed. 4. It is suggested that the myelin-like fraction is a stage in the formation of compact myelin from glial plasma membrane. 5. `Early' myelin consists of the myelin-like and compact myelin fractions from developing brain.

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