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The determinants of periorbital skin ageing in participants of a melanoma case-control study in the U.K.

Authors
  • Suppa, M1
  • Elliott, F
  • Mikeljevic, J S
  • Mukasa, Y
  • Chan, M
  • Leake, S
  • Karpavicius, B
  • Haynes, S
  • Bakker, E
  • Peris, K
  • Barrett, J H
  • Bishop, D T
  • Newton Bishop, J A
  • 1 Section of Epidemiology and Biostatistics, Leeds Cancer Research UK. [email protected]
Type
Published Article
Journal
British Journal of Dermatology
Publisher
Wiley (Blackwell Publishing)
Publication Date
November 2011
Volume
165
Issue
5
Pages
1011–1021
Identifiers
DOI: 10.1111/j.1365-2133.2011.10536.x
PMID: 21787368
Source
Medline
License
Unknown

Abstract

Periorbital wrinkling is a poor biomarker of reported sun exposure. Vascularity is a better biomarker as is blotchy pigmentation, the latter in darker-skinned individuals. In summary, male sex, sun exposure, smoking, obesity and MC1R variants were associated with measures of cutaneous ageing. Sunscreen use showed some evidence of being protective.

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