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The case for outpatient treatment of Plasmodium falciparum malaria in a selected UK immigrant population.

Authors
  • Melzer, Mark1
  • Lacey, Sandra
  • Rait, Greta
  • 1 King George and Queen's Hospitals, Barking, Havering and Redbridge Trust, Barley Lane, Goodmayes, Essex IG3 8YB, UK. [email protected]
Type
Published Article
Journal
The Journal of infection
Publication Date
October 2009
Volume
59
Issue
4
Pages
259–263
Identifiers
DOI: 10.1016/j.jinf.2009.08.010
PMID: 19706306
Source
Medline
License
Unknown

Abstract

UK guidance recommends that all patients with falciparum malaria be admitted to hospital, although a number of cohort studies in the developed world demonstrate that outpatient treatment of falciparum malaria is feasible and safe in selected patients. We review the literature on outpatient treatment in developed countries and present local data from East London where a selected immigrant population were successfully treated as outpatients. Although it is premature to claim that outpatient treatment of falciparum malaria is safe in all selected patients, we conclude it is time for a large UK-based safety study or randomised trial to dispel the belief that all patients with uncomplicated Plasmodium falciparum must be admitted to hospital.

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