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[Tetanus immunity during senescence (author's transl)].

Authors
  • Finger, H
  • Habermann, E
  • Bracharz, K
  • Hof, H
Type
Published Article
Journal
Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe B: Hygiene, präventive Medizin
Publication Date
Oct 01, 1975
Volume
161
Issue
2
Pages
188–193
Identifiers
PMID: 1189803
Source
Medline
License
Unknown

Abstract

The circulating concentrations of antibodies directed against tetanus toxoid were determined by means of the mouse protection test in the serum samples of 2554 patients with an age between 60 and 98 years. Additionally, a part of the sera was tested by a radioimmunologic procedure. Immunity (neutralizing antitoxin titer greater than or equal to 0.01 International Units/ml serum) was only demonstrable in a small percent of the samples (15.3%). Compared to women, a larger percentage of men were found to be protected. Active immunization of aged persons (60-93 years old) resulted in the finding that usually also during senescence powerful immunity may develop following suitable vaccination.

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