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Testosterone dose-response relationships in hysterectomized women with or without oophorectomy: effects on sexual function, body composition, muscle performance and physical function in a randomized trial.

Authors
  • Huang, Grace
  • Basaria, Shehzad
  • Travison, Thomas G
  • Ho, Matthew H
  • Davda, Maithili
  • Mazer, Norman A
  • Miciek, Renee
  • Knapp, Philip E
  • Zhang, Anqi
  • Collins, Lauren
  • Ursino, Monica
  • Appleman, Erica
  • Dzekov, Connie
  • Stroh, Helene
  • Ouellette, Miranda
  • Rundell, Tyler
  • Baby, Merilyn
  • Bhatia, Narender N
  • Khorram, Omid
  • Friedman, Theodore
  • And 2 more
Type
Published Article
Journal
Menopause The Journal of The North American Menopause Society
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
May 31, 2014
Volume
21
Issue
6
Pages
612–623
Identifiers
DOI: 10.1097/GME.0000000000000093
PMID: 24281237
Source
Medline
License
Unknown

Abstract

Testosterone administration in hysterectomized women with or without oophorectomy for 24 weeks was associated with dose and concentration-dependent gains in several domains of sexual function, lean body mass, chest-press power, and loaded stair-climb power. Long-term trials are needed to weigh improvements in these outcomes against potential long-term adverse effects.

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