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Test Characteristics of Assays to Detect Mycobacterium bovis Infection in High-Prevalence African Buffalo (Syncerus caffer) Herds.

Authors
  • Bernitz, Netanya1
  • Kerr, Tanya J1
  • de Waal, Candice1
  • Cooper, David V2
  • Warren, Robin M1
  • Van Helden, Paul D1
  • Parsons, Sven D C1
  • Miller, Michele A1
  • 1 Department of Science and Technology-National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. , (South Africa)
  • 2 Ezemvelo KwaZulu-Natal Wildlife, PO Box 25, Mtubatuba 3935, South Africa. , (South Africa)
Type
Published Article
Journal
Journal of wildlife diseases
Publication Date
Nov 21, 2019
Identifiers
PMID: 31750773
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

A herd of African buffaloes (Syncerus caffer) was tested for Mycobacterium bovis infection using three cytokine release assays. All animals were subsequently euthanized and mycobacterial culture determined the infection prevalence (52%) and diagnostic characteristics. Sensitivities were lower than previously reported and results provide new insight into the practical utility of these assays.

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