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Terahertz Time-Domain Spectroscopy of Glucose and Uric Acid

Authors
  • Upadhya, P.C.1
  • Shen, Y.C.1
  • Davies, A.G.2
  • Linfield, E.H.1
  • 1 University of Cambridge, Cavendish Laboratory, Madingley Road, Cambridge, CB3 0HE, UK , Cambridge
  • 2 University of Leeds, School of Electronic and Electrical Engineering, Leeds, LS2 9JT, UK , Leeds
Type
Published Article
Journal
Journal of Biological Physics
Publisher
Kluwer Academic Publishers
Publication Date
Jun 01, 2003
Volume
29
Issue
2-3
Pages
117–121
Identifiers
DOI: 10.1023/A:1024476322147
Source
Springer Nature
Keywords
License
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Abstract

We report the use ofterahertz time-domain spectroscopy for thestudy of two therapeutic bio-molecules:glucose and uric acid. Terahertztransmission spectra of crystalline samplesof both molecules were measured between 0.1–3.0 THz using an evacuated spectroscopysystem. We propose that the stereo-isomersof glucose show spectral featuresoriginating from intermolecular vibrationalmodes, as do uric acid and its derivativemolecule, allantoin. In addition, wepresent a full temperature dependence ofthe terahertz absorption of L-glucose.

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