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Teniposide is not effective in chronic lymphocytic leukemia.

Authors
  • Zagonel, V
  • Tirelli, U
  • Veronesi, A
  • Galligioni, E
  • Tumolo, S
  • Roncadin, M
  • Carbone, A
  • Grigoletto, E
Type
Published Article
Journal
Blut
Publication Date
Jan 01, 1986
Volume
52
Issue
1
Pages
59–61
Identifiers
PMID: 3632912
Source
Medline
License
Unknown

Abstract

Teniposide has been evaluated in a phase II clinical trial in chronic lymphocytic leukemia (CLL). Among 16 consecutive patients with CLL entered in the study and treated with Teniposide, 100 mg/m2 weekly, no objective response was observed. Toxicity was generally mild and mainly hematologic. Teniposide at this dosage and schedule is an inactive drug in CLL.

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