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Telomerase activity in patients with transitional cell carcinoma: a preliminary study.

Authors
  • 1
Type
Published Article
Journal
Cancer
0008-543X
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
85
Issue
4
Pages
919–924
Identifiers
PMID: 10091771
Source
Medline

Abstract

In this study, almost all tumor biopsies exhibited telomerase activity. The high incidence of telomerase activity found in cup biopsies of the malignant field uroepithelial cells from cup biopsies of TCC patients may suggest that telomerase could be activated early in carcinogenesis. A high incidence of telomerase activity was found in voided uroepithelial cells of TCC patients; however, no correlation between this activity and the histologic determination of grading and staging of the tumor was found.

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