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Techniques for comparison of thermal and mechanical nociceptive stimuli in the sheep.

Authors
  • Nolan, A
  • Livingston, A
  • Morris, R
  • Waterman, A
Type
Published Article
Journal
Journal of pharmacological methods
Publication Date
Mar 01, 1987
Volume
17
Issue
1
Pages
39–49
Identifiers
PMID: 3560984
Source
Medline
License
Unknown

Abstract

The assessment of analgesia in conscious unrestrained farm animals presents particular problems. In order to provide a reliable nociceptive stimulus, two devices have been constructed, one that provides a threshold reading for a ramped thermal stimulus of the pinna of the ear and another that measures a threshold reading for a pressure stimulus to the foreleg. Both devices allow the rapid termination of the stimulus once a reaction has occurred and allow repeated readings without causing tissue damage. Examples of the analgesic action of alpha 2-adrenoceptor agonists and opioids measured by using the two pieces of apparatus are shown.

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