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[Systemic sclerosis-clinical picture, diagnosis, and treatment].

Authors
  • Becker, M O1
  • Distler, O2
  • Maurer, B2
  • 1 Klinik für Rheumatologie, Universitätsspital Zürich, Gloriastrasse 25, 8091, Zürich, Schweiz. [email protected]
  • 2 Klinik für Rheumatologie, Universitätsspital Zürich, Gloriastrasse 25, 8091, Zürich, Schweiz.
Type
Published Article
Journal
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
Publication Date
Sep 01, 2019
Volume
70
Issue
9
Pages
723–741
Identifiers
DOI: 10.1007/s00105-019-4454-0
PMID: 31384958
Source
Medline
Keywords
Language
German
License
Unknown

Abstract

Systemic sclerosis is a rare rheumatologic disease that is characterised by skin and organ fibrosis as well as vascular changes and the occurrence of specific autoantibodies. It has a high morbidity and mortality while its manifestations show significant heterogeneity in patients. Thus, diagnosis and follow-up of patients with systemic sclerosis has to be extensive, the more so because treatment must be adapted to organ manifestations. Although specific therapies for gastrointestinal, pulmonary or vascular complications exist, patients respond only partly to these and new therapeutic approaches are still needed.

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