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Systemic lupus erythematosus in a patient with human immunodeficiency virus infection – challenges in diagnosis and management

Authors
  • Gould, T.1
  • Tikly, M.1
  • 1 Chris Hani Baragwanath Hospital and University of the Witwatersrand, Division of Rheumatology, Department of Medicine, Johannesburg, 2013, South Africa , Johannesburg
Type
Published Article
Journal
Clinical Rheumatology
Publisher
Springer-Verlag
Publication Date
Feb 14, 2004
Volume
23
Issue
2
Pages
166–169
Identifiers
DOI: 10.1007/s10067-003-0833-z
Source
Springer Nature
Keywords
License
Yellow

Abstract

Systemic lupus erythematosus (SLE) is mainly a disease of young women. The problem of coexistent human immunodeficiency virus (HIV) infection is a growing problem in sub-Saharan Africa. We describe a case of active life-threatening neuropsychiatric lupus in a patient with underlying HIV infection. The challenges of interpreting physical signs and laboratory features that are common to both conditions, and the dilemma of treating active SLE with cytotoxics in the immunocompromised patient, are discussed.

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