Three children had systemic immediate-type reactions to Japanese encephalitis (JE) vaccine which contains gelatin as a stabilizer. We found that all the children had anti-gelatin IgE in their sera. Further, two of the three also had experienced systemic allergic reactions to gelatin-containing foods before the vaccination. We assume that the systemic allergic reactions to JE vaccines might be caused by gelatin in the JE vaccine.
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This record was last updated on 07/02/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/9066026