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Synthesis of phosphorylated recognition marker in lysosomal enzymes is located in the cis part of Golgi apparatus.

Authors
Type
Published Article
Journal
The Journal of biological chemistry
Publication Date
Volume
257
Issue
10
Pages
5323–5325
Identifiers
PMID: 6279593
Source
Medline
License
Unknown

Abstract

Rat liver membranes were subjected to centrifugation in a sucrose density gradient in which the Golgi apparatus was separated into several subfractions. Two enzymes involved in the synthesis of the phosphorylated recognition marker in lysosomal enzymes, UDP-N-acetylglucosamine:lysosomal enzyme precursor N-acetylglucosamine-1-phosphotransferase and alpha-N-acetylglucosaminyl phosphodiesterase fractionated with alpha-1,2-mannosidase, a marker enzyme of cis Golgi membranes and differently from galactosyltransferase, a marker enzyme of trans Golgi membranes.

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