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Synthesis of beta- and gamma-carbolines by the palladium-catalyzed iminoannulation of internal alkynes.

Authors
Type
Published Article
Journal
Organic Letters
1523-7052
Publisher
American Chemical Society
Publication Date
Volume
3
Issue
20
Pages
3083–3086
Identifiers
PMID: 11574000
Source
Medline
License
Unknown

Abstract

[reaction: see text] A variety of substituted beta- and gamma-carbolines have been prepared in good to excellent yields by the annulation of internal acetylenes by the tert-butylimines of N-substituted 3-iodoindole-2-carboxaldehydes and 2-haloindole-3-carboxaldehydes, respectively, in the presence of a palladium catalyst.

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