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Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives.

Authors
  • Leroy, Frederic
  • Chaves, Dominique
  • Dukhan, David
  • Storer, Richard
  • Sommadossi, Jean-Pierre
  • Loi, Anna Giulia
  • Cadeddu, Alessandra
  • Fanti, Maura
  • Boscu, Nadia
  • Bassetti, Fabiola
  • Liuzzi, Michel
  • Gosselin, Gilles
Type
Published Article
Journal
Nucleic acids symposium series (2004)
Publication Date
Jan 01, 2008
Issue
52
Pages
595–596
Identifiers
DOI: 10.1093/nass/nrn301
PMID: 18776520
Source
Medline
License
Unknown

Abstract

Three 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives were synthesized and evaluated as potential inhibitors of RNA virus replication, including hepatitis C virus (HCV).

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