Synthesis and antiallergy activity of 4-oxopyrano[3,2-b]indoles.
- Published Article
Journal of medicinal chemistry
- Publication Date
Nov 01, 1980
A series of 4-oxopyrano[3,2-b]indole carboxylic acids, tetrazoles, and carboxamidotetrazoles has been prepared and tested for antiallergy potential in the rat passive cutaneous anaphylaxis (PCA) assay. Many of the compounds showed activity comparable or superior to that of cromolyn sodium or doxantrazole. Several compounds were orally active.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/7452677