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Synthesis and absolute configuration of a new 3,4-dihydro-beta-carboline-type alkaloid, 3,4-dehydro-5(S)-5-carboxystrictosidine, isolated from Peruvian Uña de Gato (Uncaria tomentosa).

Authors
  • Kitajima, Mariko1
  • Yokoya, Masashi
  • Takayama, Hiromitsu
  • Aimi, Norio
  • 1 Graduate School of Pharmaceutical Sciences, Chiba University, Japan. , (Japan)
Type
Published Article
Journal
Chemical & pharmaceutical bulletin
Publication Date
Oct 01, 2002
Volume
50
Issue
10
Pages
1376–1378
Identifiers
PMID: 12372867
Source
Medline
License
Unknown

Abstract

The structure including the absolute configuration of a new glucoalkaloid, 3,4-dehydro-5(S)-5-carboxystrictosidine, isolated from Peruvian Uña de Gato (Cat's Claw, original plant: Uncaria tomentosa), was confirmed by synthesis starting from secologanin and L-tryptophan.

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