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Synthesis of (3R,5R)-harzialactone A and its (3R,5S)-isomer.

Authors
Type
Published Article
Journal
Beilstein Journal of Organic Chemistry
1860-5397
Publisher
Beilstein-Institut
Publication Date
Volume
6
Pages
8–8
Identifiers
DOI: 10.3762/bjoc.6.8
PMID: 20485590
Source
Medline
Keywords
License
Unknown

Abstract

The total synthesis of (3R,5R)-harzialactone A (1) and its (3R,5S)-isomer (2) is described. Epoxide opening with thioacetal and diastereoselective reductions are used as key reactions.

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