Syntheses of new modified Phe-Pro peptides. Use of proline replacements in potential HIV inhibitors.
- Authors
- Type
- Published Article
- Journal
- Bioorganic & Medicinal Chemistry Letters
- Publisher
- Elsevier
- Publication Date
- Feb 03, 1998
- Volume
- 8
- Issue
- 3
- Pages
- 277–280
- Identifiers
- PMID: 9871669
- Source
- Medline
- License
- Unknown
Abstract
The syntheses consisting of replacement of proline amino acid by a 3-pyrrolidinone ring in Phe-Pro analogues are described. Preliminary anti-HIV studies demonstrated the potential activity of this new class of compounds.