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Syntheses of new modified Phe-Pro peptides. Use of proline replacements in potential HIV inhibitors.

Authors
  • Bouygues, M
  • Medou, M
  • Quéléver, G
  • Chermann, J C
  • Camplo, M
  • Kraus, J L
Type
Published Article
Journal
Bioorganic & Medicinal Chemistry Letters
Publisher
Elsevier
Publication Date
Feb 03, 1998
Volume
8
Issue
3
Pages
277–280
Identifiers
PMID: 9871669
Source
Medline
License
Unknown

Abstract

The syntheses consisting of replacement of proline amino acid by a 3-pyrrolidinone ring in Phe-Pro analogues are described. Preliminary anti-HIV studies demonstrated the potential activity of this new class of compounds.

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