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Synergistic antibacterial brilliant blue/reduced graphene oxide/quaternary phosphonium salt composite with excellent water solubility and specific targeting capability.

Authors
  • Cai, Xiang1
  • Tan, Shaozao
  • Lin, Minsong
  • Xie, Agui
  • Mai, Wenjie
  • Zhang, Xiuju
  • Lin, Zhidan
  • Wu, Ting
  • Liu, Yingliang
  • 1 Department of Chemistry, Jinan University, Guangzhou 510632, China. , (China)
Type
Published Article
Journal
Langmuir
Publisher
American Chemical Society
Publication Date
Jun 21, 2011
Volume
27
Issue
12
Pages
7828–7835
Identifiers
DOI: 10.1021/la201499s
PMID: 21585214
Source
Medline
License
Unknown

Abstract

A water-soluble brilliant blue/reduced graphene oxide/tetradecyltriphenylphosphonium bromide composite (BB-rGO-TTP) was prepared by using noncovalent brilliant blue-functionalized reduced graphene oxide (BB-rGO) as the tetradecyltriphenylphosphonium bromide (TTP) carrier. Antibacterial performance of this novel composite was investigated for both Gram-positive and Gram-negative bacteria. The results showed that the novel BB-rGO-TTP, combing the advantages of graphene and TTP, displayed excellent synergistic antibacterial activity, specific targeting capability, water solubility, and mild cytotoxicity, suggesting the great potential application as sprayable graphene-based antibacterial solutions.

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