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Symptom-based diagnostic approach for eosinophilic esophagitis

Authors
  • Fujiwara, Yasuhiro1
  • 1 Osaka City University Graduate School of Medicine,
Type
Published Article
Journal
Journal of Gastroenterology
Publisher
Springer Singapore
Publication Date
Jul 27, 2020
Volume
55
Issue
9
Pages
833–845
Identifiers
DOI: 10.1007/s00535-020-01701-y
PMID: 32720208
PMCID: PMC7452936
Source
PubMed Central
Keywords
License
Unknown

Abstract

The prevalence of eosinophilic esophagitis (EoE) has been increasing in Japan. Although the diagnosis of EoE is based on simple criteria that include the presence of esophageal symptoms and esophageal eosinophilia on biopsies, there are several important issues associated with the diagnostic approach. Following an extensive literature search, the symptoms of 886 EoE cases in Japanese adults were analyzed and divided into three categories as follows: (1) typical symptoms, such as dysphagia (53%); (2) other upper GI symptoms (40%); and (3) no symptoms found during screening or medical examination, i.e., “asymptomatic esophageal eosinophilia” (19%). The diagnostic approach was reviewed according to these categories as well as according to the presence or absence of esophageal eosinophilia. The present manuscript describes the current therapeutic strategy of EoE and ultimately proposes a symptom-based diagnostic approach for EoE.

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