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Sweet's syndrome with myelofibrosis and leukemia: partial response to interferon.

Authors
  • Brodkin, R H
  • Schwartz, R A
Type
Published Article
Journal
Dermatology (Basel, Switzerland)
Publication Date
Jan 01, 1995
Volume
190
Issue
2
Pages
160–163
Identifiers
PMID: 7727840
Source
Medline
License
Unknown

Abstract

Sweet's syndrome with malignancy or acute neutrophilic dermatosis (AND) is an unusual cutaneous disorder seen most commonly in association with acute myelogenous leukemia. A large majority of patients with AND and malignancy have neoplasms of hematopoietic, plasma cell or lymphoid nature. The patient reported here had myelofibrosis, chronic myelogenous leukemia and Sweet's syndrome. The individual lesions responded to intralesional interferon-alpha 2, which has not to our knowledge been reported previously. This result, however, was not as great as the response of AND to intralesional steroid injections.

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