Sustainable Land Management (SLM) represents a holistic approach to achieving long-term productive ecosystems by integrating biophysical, socio-cultural and economic needs and values. SLM is one of the main mechanisms to achieve Land Degradation Neutrality (LDN).To foster and facilitate the adoption of SLM practices that address DLDD while mitigating climate change and enhancing climate change adaptation, this report assesses the synergistic potential of SLM practices while also critically evaluating the possible trade-offs between the different objectives. The assessment provides a scientifically-sound basis to understand SLM’s potential to contribute to multiple objectives, and provides practical guidance for creating an enabling environment for selection and large-scale implementation of effective, locallyadapted SLM practices. Overall objective : The objective of the present report is to “highlight the science-based synergistic potential of SLM practices to address DLDD, climate change mitigation and adaptation” as a contribution to the UNCCD’s Science Policy Interface (SPI) work programme 2016-2017. By doing so, the linkages between SLM practices to address DLDD, climate change adaptation and mitigation, and resulting synergies and trade-offs, are considered.