Susceptibility to Colistin of Multi-Resistant Pseudomonas aeruginosa Isolated in Douala Laquintinie Hospital, Cameroon

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Susceptibility to Colistin of Multi-Resistant Pseudomonas aeruginosa Isolated in Douala Laquintinie Hospital, Cameroon

Authors
  • Noel Simon Ateba
  • Guy Pascal Ngaba
  • Cécile Okalla Ebongue
  • Rufine Octave Ngassongo
  • Jean Gustave Tsiagadigui
  • Gérard Behiya
  • Eveline Nguepi
  • Dieudonné Adiogo
Type
Published Article
Journal
African Journal of Pathology and Microbiology
Publisher
Ashdin Publishing
Volume
2
Pages
1–4
Identifiers
DOI: 10.4303/ajpm/235641
Source
Ashdin
Keywords
License
Green

Abstract

Pseudomonas aeruginosa is a germ of hospitalism responsible for nosocomial infections; it is naturally resistant to many antibiotics and has a high susceptibility to the acquisition of acquiring new resistance. The observation of strains highly resistant to antibiotics, has led us to look for possible alternative therapeutics. This study was a descriptive and cross-sectional one, conducted from October 2010 to March 2011. All patients hospitalized for at least 48 hours and showing sign of infection were included after obtaining their consent. Forty nine of 150 samples were positive to the cultivation of Pseudomonas aerug-inosa showing a prevalence of 32.66%. For the antibiotic susceptibility, we obtain amikacin 57.14%, netilmicin 59.20%, ceftazidime 52.60%, imipenem 33%, colistin 97.95%, and ciprofloxacin 51%. Seven strains were resistant to all antibiotics tested other than colistin. One strain was resistant to colistin. Colistin retains high sensitivity to Pseudomonas aeruginosa. However, there are some strains multiresistant to antibiotics .

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