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Susceptibility to murine hepatitis virus (type 3)-induced paralysis is influenced by class I genes of the MHC.

Authors
  • Oth, D
  • Lussier, G
  • Cainelli-Gebara, V C
  • Dupuy, J M
Type
Published Article
Journal
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics
Publication Date
Jan 01, 1991
Volume
18
Issue
5-6
Pages
405–410
Identifiers
PMID: 1663392
Source
Medline
License
Unknown

Abstract

Using H-2 recombinant congenic strains of mice, genetic analysis of resistance to murine hepatitis virus type 3 (MHV3)-induced paralysis was performed. It appeared that both H-2K and H-2D, two class I gene regions of the mouse major histocompatibility complex (MHC), can play independent significant roles in the establishment of such resistance.

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