Affordable Access

Susceptibility of Legionella spp. to imipenem and 27 other beta-lactam antibiotics.

Authors
  • Ruckdeschel, G
  • Ehret, W
  • Ahl, A
Type
Published Article
Journal
European Journal of Clinical Microbiology
Publisher
Springer-Verlag
Publication Date
Oct 01, 1984
Volume
3
Issue
5
Pages
463–467
Identifiers
PMID: 6594234
Source
Medline
License
Unknown

Abstract

With 28 beta-lactam antibiotics the susceptibilities of 60 strains of Legionella spp. (49 Legionella pneumophila and 11 ATCC type strains of other Legionella species) were determined. Agar dilution testing was used on buffered charcoal-yeast extract agar to which 0.1% alpha-ketoglutarate was added. The most active of the penicillins tested were ampicillin (MIC = 0.06-8 mg/l) and temocilin (MIC = 0.125 - 16 mg/l); the most active cephalosporins were ceftazidime (MIC = 0.03 - 0.5 mg/l), HR 810 (MIC = 0.06 - 1 mg/l) and cefoxitin (MIC = 0.125 - 2 mg/l). Of all the drugs tested imipenem had the most pronounced activity (MIC = .0075 - 0.06 mg/l).

Report this publication

Statistics

Seen <100 times