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Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype.

Authors
  • Uren, A G
  • Wong, L
  • Pakusch, M
  • Fowler, K J
  • Burrows, F J
  • Vaux, D L
  • Choo, K H
Type
Published Article
Journal
Current Biology
Publisher
Elsevier
Publication Date
Nov 02, 2000
Volume
10
Issue
21
Pages
1319–1328
Identifiers
PMID: 11084331
Source
Medline
License
Unknown

Abstract

In vertebrates, Survivin and INCENP have related roles in mitosis, coordinating events such as microtubule organization, cleavage-furrow formation and cytokinesis. Like their yeast homologs Bir1 and Sli15, they may also act together with the Aurora kinase.

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