Generalized herein is the authors' experience gained in surgical management of concomitant lesions of coronary and carotid arteries,followed by substantiating advantages of stagewise surgical treatment of patients suffering from coronary artery disease (CAD) combined with multifocal atherosclerotic lesions of other vascular basins. A total of 192 patients were operated on using various treatment options. Group One consisted of patients subjected to simultaneous operations (n=57), whereas Group Two comprised patients having undergone stagewise interventions (n=135). The mortality rate in the group of simultaneous procedures amounted to 7% (eight patients), with perioperative stroke being revealed in five (8.8%) patients, and perioperative myocardial infarction in three (5.3%) subjects. As for the group of stagewise operations, the lethality rate amounted to 2.2% (three patients), perioperative stroke was observed to have developed in four (2.9%) patients, and acute myocardial infarction in three (2.2%) subjects.