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Surgical Management of Metastatic Disease.

Authors
  • Keung, Emily Z1
  • Fairweather, Mark1
  • Raut, Chandrajit P2
  • 1 Department of Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
  • 2 Department of Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA; Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02115, USA. Electronic address: [email protected]
Type
Published Article
Journal
The Surgical clinics of North America
Publication Date
Oct 01, 2016
Volume
96
Issue
5
Pages
1175–1192
Identifiers
DOI: 10.1016/j.suc.2016.05.010
PMID: 27542649
Source
Medline
Keywords
License
Unknown

Abstract

Sarcomas are rare cancers of mesenchymal cell origin that include many histologic subtypes and molecularly distinct entities. For primary resectable sarcoma, surgery is the mainstay of treatment. Despite treatment, approximately 50% of patients with soft tissue sarcoma are diagnosed with or develop distant metastases, significantly affecting their survival. Although systemic therapy with conventional chemotherapy remains the primary treatment modality for those with metastatic sarcoma, increased survival has been achieved in select patients who receive multimodality therapy, including surgery, for their metastatic disease. This article provides an overview of the literature on surgical management of pulmonary and hepatic sarcoma metastases.

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