A previously healthy 36-year-old man admitted via emergency room with complaint of progressive chronic abdominal pain for 2 weeks. An enhanced computed tomography (CT) scan revealed a total occlusion of the superior mesenteric vein with thrombus and partial thrombosis of main portal vein. However, CT scan did not show any evidence of infectious or inflammatory foci in the abdominal cavity. He did not have any family history of coagulation disorder. He neither had any detectable coagulation disorder to induce thrombosis. The only possible risk factor for the superior venous thrombus is chronic inhalation exposure to stearic acid.