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Sugars and Sweeteners: Structure, Properties and In Silico Modeling.

Authors
  • Janežič, Dušanka1
  • Jäntschi, Lorentz2, 3
  • Bolboacă, Sorana D4
  • 1 Faculty of Mathematics, Natural Sciences and Information Technologies, University of Primorska, Koper, Slovenia. , (Slovenia)
  • 2 Department of Physics and Chemistry, Technical University of Cluj-Napoca, Cluj-Napoca, Romania. , (Oman)
  • 3 Chemistry Doctoral School, Babeş-Bolyai University, Cluj-Napoca, Romania. , (Oman)
  • 4 Department of Medical Informatics and Biostatistics, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. , (Oman)
Type
Published Article
Journal
Current medicinal chemistry
Publication Date
Jan 01, 2020
Volume
27
Issue
1
Pages
5–22
Identifiers
DOI: 10.2174/0929867325666180926144401
PMID: 30259809
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Several studies report the effects of excessive use of sugars and sweeteners in the diet. These include obesity, cardiac diseases, diabetes, and even lymphomas, leukemias, cancers of the bladder and brain, chronic fatigue syndrome, Parkinson's disease, Alzheimer's disease, multiple sclerosis, autism, and systemic lupus. On the other hand, each sugar and sweetener has a distinct metabolic assimilation process, and its chemical structure plays an important role in this process. Several scientific papers present the biological effects of the sugars and sweeteners in relation to their chemical structure. One important issue dealing with the sugars is the degree of similarity in their structures, focusing mostly on optical isomerism. Finding and developing new sugars and sweeteners with desired properties is an emerging research area, in which in silico approaches play an important role. Copyright© Bentham Science Publishers; For any queries, please email at [email protected]

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