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Suffocation of nerve fibers by living nanovesicles: a model simulation.

Authors
  • Sommer, Andrei P
Type
Published Article
Journal
Journal of proteome research
Publication Date
Jan 01, 2004
Volume
3
Issue
3
Pages
667–669
Identifiers
PMID: 15253453
Source
Medline
License
Unknown

Abstract

A model using nanospheres to allow the simulation of the nonspecific interaction of nanobacteria (NB), one with another or with body tissues, is established. Depending primarily on their concentrations and stress levels, these apatite nanovesicles may nucleate thrombogenic conglomerates in blood, or self-assemble to dense nanoclay layers on surfaces in the body. Partial or total encapsulation of nerve fiber bundles by such mineral layers may interrupt the metabolic exchanges between the surrounded tissue and its immediate environment and may restrict signaling processes. The presented model could provide detailed insight into plaque formation triggered by NB, and the parameters encouraging it.

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