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Sudden death risk markers for patients with left ventricular ejection fractions greater than 40

Authors
  • Halliday, BP
  • Lota, AS
  • Prasad, SK
Publication Date
May 02, 2018
Source
Spiral - Imperial College Digital Repository
Keywords
Language
English
License
Unknown
External links

Abstract

The major burden of sudden cardiac death (SCD) in patients with heart disease occurs in those with a left ventricular ejection fraction > 40%. Although the annual risk of SCD may be lower in these patients compared to those with lower LVEF, their lifetime cumulative risk of SCD may be greater due to a better overall prognosis. It is plausible that those with LVEF > 40% who are at highest risk of life-threatening arrhythmia will benefit from implantable cardioverter defibrillators. Features that identify patients with a LVEF > 40% at high risk of SCD are urgently needed. We review existing studies examining SCD markers in this sub-group and discuss gaps in the current evidence base.

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