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Sucrose concentration influences the rate of human oocytes with normal spindle and chromosome configurations after slow-cooling cryopreservation.

Authors
Type
Published Article
Journal
Human Reproduction
0268-1161
Publisher
Oxford University Press
Publication Date
Volume
21
Issue
7
Pages
1771–1776
Identifiers
PMID: 16549422
Source
Medline

Abstract

Partial disruption of the MII spindle and associated chromosomes accompanies inadequate cryopreservation during slow cooling. However, protocols adopting higher sucrose concentration in the freezing solution promote the retention of an intact chromosome segregation apparatus comparable in incidence to freshly collected oocytes.

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