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Successful treatment of a Streptococcus pneumoniae- associated haemolytic uraemic syndrome by eculizumab

Authors
  • Jeantet, Guillaume
  • Pernin, Vincent
  • Brunot, Vincent
  • Roccabianca, Arnaud
  • Macombe, Anouk
  • Szwarc, Ilan
  • Klouche, Kada
  • Loirat, Chantal
  • Mourad, Georges
  • Fremeaux-Bacchi, Veronique
  • Le Quintrec, Moglie
Publication Date
Feb 01, 2019
Source
HAL-INRIA
Keywords
Language
English
License
Unknown
External links

Abstract

Haemolytic uraemic syndrome (HUS) is a rare complication of invasive infection by Streptococcus pneumoniae (SP-HUS), especially in adults. Here we report an unusual case of a 53-year-old man presenting SP-HUS with severe multivisceral involvement. After failure of supportive care and plasma exchanges, eculizumab (anti-C5 antibody) resulted in a favourable outcome.

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