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Successful treatment of metastatic esthesioneuroblastoma.

Authors
  • de Vos, F Y F L
  • Willemse, P H B
  • de Vries, E G E
Type
Published Article
Journal
The Netherlands journal of medicine
Publication Date
Dec 01, 2003
Volume
61
Issue
12
Pages
414–416
Identifiers
PMID: 15025418
Source
Medline
License
Unknown

Abstract

This case report describes a patient with a metastasised olfactorial esthesioneuroblastoma Hyams grade 4 who has been treated with debulking surgery and radiotherapy. After relapse in lymph node, lung and brain, he received additional irradiation and six cycles of carboplatin, vincristine and cyclophosphamide intravenously every three weeks. The patient has now been disease free for 7.8 years. Our data suggest that metastatic esthesioneuroblastoma is sensitive to platinum-based chemotherapy. This patient illustrates that this tumour is very sensitive to platinum-based chemotherapy and that durable complete response can be achieved, even in a metastatic ENB.

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