Substrates of PHD
- Authors
- Type
- Published Article
- Journal
- Cell metabolism
- Publication Date
- Oct 01, 2019
- Volume
- 30
- Issue
- 4
- Pages
- 626–627
- Identifiers
- DOI: 10.1016/j.cmet.2019.08.008
- PMID: 31577931
- PMCID: PMC7454164
- Source
- PubMed Central
- License
- Unknown
Abstract
The discovery of prolyl hydroxylase domain proteins (PHDs) as key enzymes in the hypoxia inducible factor (HIF) pathway has been followed by reports of a multitude of non-HIF substrates of PHD. Reporting in eLife , Cockman et al. (2019) find a surprising lack of detectable PHD activity toward any of them.
