Objective. We report a complication of endoscopic Zenker's diverticulum repair after postoperative continuous positive airway pressure (CPAP) use. Study design. Case report and literature review. Results. Patient presented for Zenker's diverticulum repair. He was treated endoscopically with gastrointestinal anastomosis stapler and carbon dioxide laser myotomy. He inadvertently resumed CPAP use early on postoperatively and subsequently presented with dysphagia. Imaging revealed subcutaneous emphysema. Conclusion. It is important to understand the implications that CPAP can have on recovery from Zenker's diverticulum repair. It is reasonable to screen all surgical candidates for CPAP use and ensure they understand instructions regarding safe postoperative use.