Affordable Access

Subarachnoid-pleural fistula as a complication of malignant pleural mesothelioma.

Authors
  • Heyer, Christoph M
  • Theile, Anja
  • Weisser, Heike
  • Reichert, Joseph
  • Horch, Christoph
  • Mueller, Klaus-M
  • Bauer, Torsten T
Type
Published Article
Journal
Respirology (Carlton, Vic.)
Publication Date
Jul 01, 2006
Volume
11
Issue
4
Pages
502–505
Identifiers
PMID: 16771925
Source
Medline
License
Unknown

Abstract

We report a 62-year-old male patient with asbestos-related malignant pleural mesothelioma who developed recurrent pleural effusions after surgical resection of paravertebral tumour masses. Pleural effusions were drained on several occasions with the patient suffering severe headaches and vascular dysregulation. Cytological studies of the pleural fluid showed no evidence of inflammatory or malignant cells. The fluid was interpreted as seroma despite its unusual transparency until magnetic resonance imaging was suggestive of a subarachnoid-pleural fistula; its presence was confirmed when beta-trace protein--a specific marker for cerebrospinal fluid--was added to the standard laboratory testing of the pleural effusion. A subarachnoid-pleural fistula has to be included in the differential diagnosis of patients with recurrent pleural effusions after surgical debulkment of malignant pleural mesothelioma. The beta-trace protein may help to establish this diagnosis especially in cases where important therapeutic consequences may need to be drawn.

Report this publication

Statistics

Seen <100 times