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Study on the Role of Vitamin D in Systemic Lupus Erythematosus

Authors
  • Jiadian, Wang
  • Muzi, Cui
  • Siyi, Wang
  • Xiao, Xue
  • Kerong, Ren
  • Zhi, Lu Li
  • Saijia, Li
  • Pingping, Yan
Journal
Journal of Advances in Medicine Science
Publisher
Bilingual Publishing Co
Publication Date
Jan 30, 2021
Volume
4
Issue
1
Identifiers
DOI: 10.30564/jams.v4i1.2728
Source
Bilingual Publishing
Keywords
License
Green

Abstract

Vitamin D is a hormone precursor with multiple biological effects. It binds to vitamin D receptors on target cells. It is an important participant in the metabolism of calcium and phosphorus in vivo. It is closely related to cell cycle, cell proliferation, differentiation, apoptosis, signal transduction and immune regulation. Its role in the treatment of infection, tumor and even immune diseases has been gradually recognized and studied. Patients with systemic lupus erythematosus generally have decreased levels of active vitamin D, and low levels of vitamin D are associated with disease occurrence, disease activity and complications. In the past ten years, a large number of studies have been carried out on it globally to explore the role of vitamin D in the occurrence and development of systemic lupus erythematosus. This paper summarizes its recent research progress.

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